* item room, treasure room, item room pool, money is power, dollar, red, grey, gray, Tears now have a random chance to freeze enemies in place, The chance to freeze enemies is affected by your luck stat, Chance to activate increases with luck, up to around 50% chance at +20 luck, UNLOCK: Unlock this item by collecting 3 'Mom' items in one playthrough, * item room, treasure room, item room pool, dungeon room, blood challenge room, arena pool, Rotten Baby becomes larger . All your items and consumables are temporarily removed while in the abandoned mine, The room to access Knife Piece 2 only appears if you have Knife Piece 1 already, You can skip pressing the 3 yellow buttons if you have the ability to fly and have 2 bombs to force open the door, When combined with Knife Piece 1, can be used to stab the fleshy door in the Mausoleum II, which then leads to the Corpse floor and the Mother boss, This is a one time use item that teleports you to an alternate floor, which contains every single item in the game, The items are spread between several different rooms all on pedestals. ), *, money, silver, grey, gray, steam, smoke, cent, Everytime you pick up a coin, you have a 25% chance to spawn a key, *, white, grey, gray, coin, cent, money, cash, When picking up a coin, you have a chance to automatically gain one more coin, UNLOCK: Unlock this item by playing the shell game in the arcade 100 times, *, yellow, golden, coin, cent, money, cash, sparkle, When you enter a boss room, immediately remove 15% health from the boss and restore 1 red heart, This trinket cannot be dropped by holding the drop key or picking up other trinkets. Only stat effects are applied; otherwise overridden by Brimstone: PC 39W8 NGWZ (Red Chest on Curse Room adjacent to spawn) Bombs, keys, cards, runes and batteries have a 20% chance, Can lead to game-breaking combinations with the D20 due to the amount of consumables and batteries spawned by the item sacks, REPENTANCE - Added to the Secret Room pool. brown, brass, copper, dads key, dad key, * boss room pool, boss room item, item room, treasure room, item room pool, lumpy, red, balls, Using the portable slot takes a coin and has a chance to give a pickup - similar to how the normal slot machines work, REPENTANCE - The delay between uses was removed, allowing you to spam-use it, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, box, yellow, grey, When used, converts 1 soul/black heart into 1 red heart container, This item will take from your soul hearts first, REPENTANCE - Converter now only costs one soul heart to use (previously costed two), * shop room pool, shop item pool, the lost item pool, blue, gray, grey, yellow, sprocket, When used, this item will spawn a set of items or consumables based on which chapter you are currently on, Basement 1: 2 Soul hearts. Supper = +0.5 tears, +1 luck. *, blue, baby, grow, headless, golden chest pool, gold chest pool, Isaac's tears become coins and now have a 5% chance to drop pennies on the floor upon successfully hitting an enemy, Has a chance to drop when exploding a dead shopkeeper, A familiar blue fly that will follow Isaac's movement pattern but delayed by 1 second, Papa Fly will fire tears at nearby enemies that deal damage equal to Isaac's tear damage, A familiar baby that will follow your movement pattern on a 2 second delay, Tears that pass through the baby will double up and gain x1.33 speed boost, Isaac's normal bombs become pink and causes them to drop random pickups when they explode (e.g. Isaac doesn't take damage from this effect, UNLOCK: Unlock this item by defeating Delirium as Tainted Lost, Spawns a familiar that's attached via an Umbilical Cord, but will move and shoot in the same direction Isaac is shooting, When activated you first need to throw the familiar, which deals x3 your tear damage to any enemies it touches, Gello's tears deal x0.75 your tear damage (x1.0 if Lilith), Can be used multiple times per room to spawn more familiars, however they only last for the current room, UNLOCK: Unlock this item by defeating Delirium as Tainted Lilith, When used, this item allows you to throw your head where it will sit as a stationary sentry firing bullets until you walk over and pick it up again, Throwing Isaac's head deals 24 damage to anything it hits while being thrown, Your hitbox remains with the body. Holding the "drop" button lets Isaac move independently from Lil Clot. devil room pool, devil deal, grey, gray, hood, Isaac now has a small chance to create friendly attack spiders everytime he fires a tear, Can create up to a maximum of 5 spiders in the room at one time, The Hive Mind item allows Mom's Wig to spawn a maximum of 10 spiders at once, and increases their damage, The chance to create a spider is affected by your luck stat and at +10 Luck it will activate every time, * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, PC 4AA3 QSMJ (Treasure Room adjacent to spawn), PC S9CH XAMT (Treasure Room adjacent to spawn), PS4 VXMQ Y96F (First Treasure Room adjacent to spawn), Achievements The Lost starts with this item after donating 879 coins to the Greed Donation Machine. While firing tears the water will be fired as a projectile across the room. Replacing all 12 containers with broken hearts will kill you instantly. Poison deals 5 damage initially and then 3.5, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Isaac, REPENTANCE - GB Bug is now a thrown projectile, activated by double tapping an attack button. Bad Trip becomes Balls of Steel. poop, pots), Counts as 1 of 3 cat items needed towards the Guppy transformation, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Cain, Item Pool: Devil Room, Curse Room, Red Chest, Spawns a Keeper familiar, that shoots triple tears and follows your exact movements as you walk, The keeper has 3 health coins and can die if it takes enough damage. Blood clotting becomes a problem when it blocks your blood . * boss room pool, boss room item, brown, leather, bag, sack, golden chest pool, gold chest pool, Gives 3-6 blue attack flies when picked up, Item Pool: Boss Room, Challenge Room, Gold/Stone Chest, Mom's Chest, * dungeon room, blood challenge room, arena pool, boss room pool, boss room item, panties, REPENTANCE - Using this book once before the boss dies, causes the boss item on the current floor to become a devil deal instead, where it will cost heart containers to pick up. Items: Rocket in a Jar, Goat Head, Dead Cat, Soy Milk, Blood Clot. orange, moms wig, Gives a chance to heal 1/2 a red heart every time the in-game timer hits a new minute, There are no restrictions on when the regeneration effect happens as long as the game is not paused, so you can simply afk and heal over time, It's possible to find this item by blowing up Polyps (the weird red rocks found in the Womb floors), * boss room pool, boss room item, the lost item pool, purple, red, lump, When you get hit, you will sometimes cause hearts to drop on the floor, The chance to drop hearts is affected by your luck stat and at +29 Luck it will activate 50% of the time, * boss room pool, boss room item, the lost item pool, plasters, white, Everytime a bomb explodes, it will release a circle of 10 tears outwards, much like the Tammy's Head effect, The tears from each bomb deal a flat 25 damage and are affected by any tear modifiers Isaac has, The tears caused by Sad Bombs are much larger and do a lot more damage than Isaac's normal tears, * boss rush pool, boss rush room, item room, treasure room, item room pool, crying, face, Isaac's tears now bounce off walls and objects in the environment, such as rocks and pots, Allows tears to hit the same enemy multiple times, If you also have Lost Contact, tears will bounce off enemy projectiles instead of being destroyed, UNLOCK: Unlock this item by beating Mom's heart 2 times, * item room, treasure room, item room pool, orange, brown, bottle, jar, As you hold down the fire button, shots will float in the same place until you release the fire key again, Allows you to store up a lot of tears in the air and release them all at once, When the tears are released, they will fire off in the direction that Isaac was originally facing when it was created, * anti gravity, item room, treasure room, item room pool, anti gravity, atom, nucleus, All explosions now heal Isaac for 0.5 red hearts instead of hurting him, REPENTANCE - Pyromaniac now grants Isaac immunity to fire, but no longer protects against stomps or shockwaves. ?, Satan and The Lamb as Tainted Jacob, Gives you a familiar that follows Isaac's exact movements (similar to how Jacob & Esau work) and shoots spectral tears, Similar to Jacob and Esau, positions can be altered by running it into objects, or holding the drop button (Ctrl on Steam version), When you place a bomb, the Found Soul will drop one too, If it takes any damage, it will die and not respawn until the next floor, UNLOCK: Unlock this trinket by defeating Mother as Tainted Jacob, Everytime you use your active item, you have a chance to activate another random active item, Glowing Hourglass effect is blocked from this item, UNLOCK: Unlock this trinket by defeating Isaac, ?? Also got libra but just a basic all stats up. This gives Isaac a bone sword and he goes on a killing rampage, gaining +0.4 Speed, +3 Flat Damage Up, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Samson, Activates the Mega Blast item effect, which gives you a giant laser that deals x5 your tear damage per tick to anything in its path and pushing Isaac back by the force, The effect lasts for 8 seconds but does persist between rooms, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Azazel, When used this kills Isaac and revives him with 1/2 a red heart. For Items it increases by 2 coins * the number of purchases. It appears as an alchemical symbol for sulfur. "I am very excited to get out on the road," says the 27-year . Transcendence The Compass PHD Rosary XRay Vision Lucky Foot Magneto Treasure Map The Ladder Charm Of The Vampire The Battery Steam Sale Dead Cat Lord Of The Pit Spelunker Hat Mr. Mega The Wafer 9 Volt Bobby-Bomb This allows you to choose between the item that originally spawned and a HP upgrade every time, This effect applies to most items, including those in the shop and devil room. are now magnetically attracted to Isaac's tears, Can cause some enemies to have unpredictable movement, * item room, treasure room, item room pool, grey, gray, magnet, Tears are now charged up and fired rapidly in a burst of up to 5 shots at once, The amount of tears fired in the charge depends on how long you charge for, The eye has three states, white (not firing), black (first second of charging) and blinking between black and white. Isaac appears demonic with large curved horns and an angry expression. These ticks occur every 1/15th of a second (once every 4 frames). UNLOCK: Unlock this item by defeating The Beast as ??? Chapters Boosts speed, range, shot speed, tears and damage if they are above their base values by roughly +20%, Affects stat bonuses from passive items, trinkets that are absorbed or in a second trinket slot, and permanent bonuses given by items such as Void, UNLOCK: Unlock this trinket by getting a 5-win streak in daily challenges (must have a score of above 0 on the score screen), While held, gives the Skatole effect only in certain rooms, which will turn hostile flies to neutral and stop others from shooting, Attack, Dart and Ring Flies turn into neutral Black Flies and Pooters and Fat Flies will no longer fire at you, Items and trinkets which generate blue flies and spiders will have double the effect, causing twice as many to spawn, *, grey, gray, green, arrow, flower, plant, Some tears will randomly become a black tooth, that deal double your normal tear damage and can poison enemies, Tears become spectral and travel in a huge spiral pattern, Every time you take damage you have a very small chance to gain a Tonsil familiar, which follows you and blocks enemy projectiles, This effect can happen twice before the Tonsil trinket is destroyed, Your tears have a random chance to become booger tears, Booger tears stick on to enemies and deal periodic poison damage until they die or 60 seconds passes. 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